Menopause might be delayed indefinitely, suggests new Utah research

Published On 2024-02-18 12:00 GMT   |   Update On 2024-02-20 12:07 GMT

At birth, ovaries in girls can contain about a million tiny structures called primordial follicles, each of which contains an egg cell. As girls grow and experience adulthood, most of these follicles will die while only one follicle will survive each month to ovulate a mature egg. When the loss of primordial follicles is nearly complete, and only hundreds remain, women experience menopause,...

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At birth, ovaries in girls can contain about a million tiny structures called primordial follicles, each of which contains an egg cell. As girls grow and experience adulthood, most of these follicles will die while only one follicle will survive each month to ovulate a mature egg. When the loss of primordial follicles is nearly complete, and only hundreds remain, women experience menopause, a time when menstrual cycles have ceased for 12 months.

Johnson J, Lawley SD, Emerson JW, Oktay KH. Modeling delay of age at natural menopause with planned tissue cryopreservation and autologous transplantation. Am J Obstet Gynecol. 2024 Jan 4:S0002-9378(24)00003-6. doi: 10.1016/j.ajog.2023.12.037. Epub ahead of print. PMID: 38184290.

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