Meta-Analysis Confirms COVID-19 Vaccination in Pregnancy Protects Both Mother and Baby Safely

For the study, the author conducted a systematic search where she included 23 meta-analyses inclusive of over 200 studies and 1,250,000 pregnant individuals with documented COVID-19 vaccination.

We found that the COVID-19 vaccination during pregnancy offers significant protections to newborns and mothers,” said Nikan Zargarzadeh, study author and Harvard University research fellow. “This information can help support informed decision-making for pregnant individuals and their care teams.”

The review found those who received a COVID-19 vaccination during pregnancy had an 8% lower risk of preterm birth before 37 weeks and a 34% lower risk of preterm birth before 28 weeks. Vaccination was also associated with an 25% lower risk of stillbirth and an 9% lower risk of neonatal intensive care admission, as well as a 17% lower risk of congenital anomalies, according to the study abstract. There were no increased risks observed for maternal hospitalization, intensive care admission, gestational diabetes, hypertension, or pre-eclampsia.

Ref: Meta-analysis: COVID-19 vaccination during pregnancy is safe and beneficial for mother and infant; American Academy of Pediatrics