Myo inositol effective in preventing gestational diabetes

 India is the Diabetes capital of the world with 10-14% of pregnant women with diabetes. A meta-analysis in European journal of Obstetrics and gynaecology aims to study the efficacy of myo-inositol supplementation for the prevention of gestational diabetes.

The study found that Myo-inositol supplementation can be recommended to prevent gestational diabetes with some caution exercised.

Several databases including PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systemically searched from inception to October 2021, and were included in the randomized controlled trials (RCTs) assessing the effect of myo-inositol supplementation on the incidence of gestational diabetes.

The study used seven eligible RCTs were included in this meta-analysis. Compared with control group in pregnant women, myo-inositol supplementation could lead to remarkably reduced incidence of gestational diabetes, reduced 2-h glucose OGTT ,increased gestational age at birth and decreased incidence of preterm delivery ,but exhibited no obvious influence on birth weight.

The researchers concluded that Myo-inositol supplementation is recommended to prevent gestational diabetes with caution due to some heterogeneity.