Burkitt's Lymphoma with an Unusual Cardiac Involvement

Written By :  Dr. Nandita Mohan
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2022-09-12 03:30 GMT   |   Update On 2022-09-12 03:30 GMT
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Let me elaborate on the case report. A 13-year-old Muslim boy of Malda (West Bengal) presented with complaints of insidious onset dull aching intermittent abdominal pain and a right-sided neck swelling for 3 months. There was no associated history of fever, rash, anorexia, weight loss, chest pain, palpitations, shortness of breath, or syncope. There was no history of similar illnesses or any chronic diseases in the past. The boy had a normal developmental and birth history. There was no history of consanguinity in the family.
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Abdominal sonography was done and it revealed a hypoechoic space occupied lesions occupying the left flank of retroperitoneal origin and multiple enlarged para-aortic lymph nodes. Mild ascites were present. Another hypoechoic space occupied lesions was present at level III of the right side of the neck with partial necrosis and extending up to the right parotid gland. A (2.8 × 1.4 cm) hypoechoic space occupied lesions was incidentally detected at the right atrial wall.
Scrotal sonography showed bilateral testicular enlargements with multiple, vascular, and hypoechoic lesions with distortion of the testicular architecture. Echocardiography was done showing multiple heterogeneous space occupied lesions arising from the interatrial septum.
Histopathologic ally, tumor cells typically had round and oval nuclei and two to five distinct nucleoli. High rates of proliferation and apoptosis were characteristic. Macrophages containing ingested nuclear debris were surrounded by a clear space creating a "starry" sky pattern.
Clinical features and investigations of this case were correlating to Burkitt's lymphoma but cardiac involvement as interatrial septal mass was considered a rare occurrence.
Reference: Bhaumik S, Chatterjee NK, Masud Reza MA, et al. Burkitt's Lymphoma with an Unusual Cardiac Involvement: A Case Report. J Assoc Physicians India 2022;70(9):85–87.
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Article Source : Journal Association Physicians India

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