Should clinicians reconsider standard therapy for gout?
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-07-09 04:00 GMT | Update On 2022-07-09 04:00 GMT
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Gout occurs when urate crystals accumulate in the joints, and xanthine oxidase inhibitors such as febuxostat are a mainstay of therapy to help reduce blood urate levels in affected patients. A recent clinical trial published in Arthritis & Rheumatology has found that low doses of a less commonly used drug called benzbromarone may be a better option, however.
In the prospective single-center, open-labeled trial, 196 men with gout and low urinary excretion of uric acid were randomized to receive low-dose benzbromarone (LDBen) or low-dose febuxostat (LDFeb) for 12 weeks.
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