Circadian rhythm common among mental health disorders: Research
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-09-03 03:45 GMT | Update On 2022-09-03 07:22 GMT
Anxiety, autism, schizophrenia and Tourette syndrome each have their own distinguishing characteristics, but one factor bridging these and most other mental disorders is circadian rhythm disruption, according to a team of neuroscience, pharmaceutical sciences, and computer science researchers at the University of California.In an article published recently in the Nature journal...
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Anxiety, autism, schizophrenia and Tourette syndrome each have their own distinguishing characteristics, but one factor bridging these and most other mental disorders is circadian rhythm disruption, according to a team of neuroscience, pharmaceutical sciences, and computer science researchers at the University of California.
In an article published recently in the Nature journal Translational Psychiatry, the scientists hypothesize that circadian rhythm disruption or CRD is a psychopathology factor shared by a broad range of mental illnesses and that research into its molecular foundation could be key to unlocking better therapies and treatments.
The researchers that said an important unresolved issue centers on the causal relationship between CRD and mental health disorders: Is CRD a key player in the origin and onset of these maladies or a self-reinforcing symptom in the progression of disease?
To answer this and other questions, the UCI-led team suggests an examination of CRD at the molecular level using transcriptomic (gene expression) and metabolomic technologies in mouse models.
Ref:
Pierre Baldi et al, The hidden link between circadian entropy and mental health disorders, Translational Psychiatry, DOI: 10.1038/s41398-022-02028-3
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