TyG index closely associated with progression of depression

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2023-01-19 03:30 GMT | Update On 2023-01-19 03:30 GMT

A recent study published in the Journal of Nutrition, Metabolism, and Cardiovascular Diseases found that baseline triglyceride glucose (TyG) index is closely associated with progression of depression. Also, from a metabolic perspective, TyG index monitoring requires more attention for mental health managements.

Cerebral symptoms are common among individuals with non-communicable conditions, while the longitudinal association between triglyceride glucose (TyG) index, indicator of metabolic health, and progression of depression remains unclear. So, this study by Lan Zheng and team aimed to check the association of birth TyG indicator and depression progression in middle-aged and elder grown-ups.

This retrospective cohort study was from the National China Health and Retirement Longitudinal Study and it included 8287 participants over 45 years out of which 45.9% were men.

The results showed that there was no significant difference of depression score at baseline across TyG quartile groups. Compared to those in the lowest, participants in the highest quartile of TyG index had a 0.124 higher change rate of depression score, and a 0.127 higher change slope.

The findings of this study strongly suggest that TyG index is positively associated with progression of depression specially in men, the elders and in obese people, this new insights might help in the primary prevention of depression.

Reference:

Zheng, L., Cui, C., Yue, S., Yan, H., Zhang, T., Ding, M., Sun, Q., He, C., & Ren, H. (2022). Longitudinal association between triglyceride glucose index and depression progression in middle-aged and elder adults: A national retrospective cohort study. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD. https://doi.org/10.1016/j.numecd.2022.11.015

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Article Source : Journal of Nutrition, Metabolism, and Cardiovascular Diseases

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Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

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TyG index closely associated with progression of depression

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