Preoperative antibiotics tied to increased risk of infection after radical cystectomy

In a new study conducted by Craig V. Labbate and the team, it was shown that outpatient antibiotic usage is prevalent prior to radical cystectomy and may be related to an increase in the risk of postoperative infection and readmission. The findings of this study were published in Urology.

The following work was conducted with an objective to assess antibiotic exposure rates before radical cystectomy and whether there is an association with postoperative infections. In order to achieve the study goal, in the 2016 SEER-Medicare linkage, 2248 patients with complete prescription information who underwent radical cystectomy between 2008 and 2014 were found. Exposure was defined as an outpatient prescription for an antibiotic within 30 days of the cystectomy. The antibiotic class and combinations were documented. Within 30 days following cystectomy, infection diagnoses and readmissions were recorded.

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Preoperative Antibiotics Tied To Increased Risk Of Infection After Radical Cystectomy: Study