Omeprazole leads to erectile dysfunction in healthy young adult:Case Study

Several factors of this patient's clinical history create a compelling argument implicating omeprazole as a potent precipitant of ED. These include:

• The temporal relationship of the onset of ED with the initiation of omeprazole therapy, the prompt resolution of symptoms following discontinuation of the drug.
• The absence of other readily apparent precipitating factors, and the absence of recurrent ED in the 2 years following the episode.

However, the researcher concluded that further study of erectile dysfunction as an adverse effect of proton pump inhibitors is required. In the meantime, proton pump inhibitors should be considered as a potential cause of erectile dysfunction in healthy young patients and as a cause or contributor to erectile dysfunction in older patients in whom erectile dysfunction is often attributed to age or comorbidities.

Reference:

Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report by Theodore W. Perry published in the Journal of Medical Case Reports

DOI: 10.1186/s13256-021-02981-5