Gold nanoparticles may help develop new obesity medicine
Biosynthesis of gold nanoparticles from medicinal plants has become an interesting strategy in biomedical research. Korean researchers believe to have discovered a synthetic gold-based compound which may help patients with obesity.
The team led by Sunoh Kim, Deok-Chun Yang at Bioresources and Technology and Kyung Hee University, South Korea, respectively, investigated the anti-lipid accumulation effect of spherical gold nanoparticles (10-20 nm in size) synthesized from Dendropanax morbifera Léveille - a shrub which is endemic to the Korean peninsula.
The nanoparticles, dubbed D-AuNPs, were tested in both 3T3-L1 and HepG2 cell lines, which are two known candidates for studying obesity and related disease models.
Research into gold nanoparticles is increasingly gaining the attention of researchers due to a rare combination of their potential medicinal benefits and environmental friendly implications. The team introduced a cocktail of the synthetic compound into 3T3-L1 preadipocytes and HepG2 hepatocytes.
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