73 percent Decline in COVID-19 incidences with Prophylactic use of Ivermectin: AIIMS Bhubaneshwar Research

Exposure was defined as the intake of ivermectin and/or hydroxychloroquine and/or vitamin-C and/or other prophylaxis for COVID-19. Data collection and entry was done in Epicollect5, and analysis was performed using STATA version 13. Conditional logistic regression models were used to describe the associated factors for COVID-19 infection.

Ivermectin prophylaxis was taken by 77 controls and 38 cases. The authors found that Two-dose ivermectin prophylaxis was associated with 73% reduction of COVID-19 infection among healthcare workers for the following one month, those who were involved in physical activity for more than an hour/day were more likely to contract COVID-19 infection. Type of household, COVID duty, single-dose ivermectin prophylaxis, vitamin-C prophylaxis and hydroxychloroquine prophylaxis were not associated with COVID-19 infection.

The authors concluded that Two-dose ivermectin prophylaxis at a dose of 300 μg/kg with a gap of 72 hours was associated 73% reduction of COVID-19 infection among healthcare workers for the following one-month

The study is currently under pre-print is yet to be peer-reviewed. This finding can be helpful in many cases where drugs like Hydroxychloroquine is contraindicated like certain cardiac conditions.

For further details click on the following link

https://www.medrxiv.org/content/10.1101/2020.10.29.20222661v1