84 percent higher risk of cardiac-related death among males 18-39 years with MRNA vaccine: Analysis sparks fear against Pfizer, Moderna Vaccine

New Delhi: Creating a scare among the patients world-wide taking the mRNA-based COVID vaccine, a recent advisory has been released by the Florida Department of Health in the US recommending against the COVID-19 mRNA vaccines for males ages 18-39 years old

 This came after a recent analysis done by the Florida Department of Health (Department) revealed that there is an 84% increase in the relative incidence of cardiac-related death among males 18-39 years old within 28 days following mRNA vaccination, whereas non-mRNA vaccines were not found to have these increased risks among any population.

This sparked fears among patients worldwide receiving mRNA-based COVID vaccines such as Pfizer-BioNTech and Moderna.

In that case, it is worth notifying that Pfizer-BioNTech and Moderna are mRNA COVID-19 vaccines whereas COVAXIN, India's indigenous COVID-19 vaccine is developed using Whole-Virion Inactivated Vero Cell derived platform technology and Covishield Vaccine contains a non-replicating virus (a weakened chimpanzee adenovirus that causes common cold), that is genetically engineered to produce coronavirus proteins in the body, but the virus is weakened and cannot cause the disease.

The observation came after the Florida Department of Health (Department) conducted an exit disclaimer icon analysis through a analysis self-controlled case series, which is a technique originally developed to evaluate vaccine safety.

This analysis found that there is an 84% increase in the relative incidence of cardiac-related death among males 18-39 years old within 28 days following mRNA vaccination.

With a high level of global immunity to COVID-19, the benefit of vaccination is likely outweighed by this abnormally high risk of cardiac-related death among men in this age group. Non-mRNA vaccines were not found to have these increased risks.

"Today, we released an analysis on COVID-19 mRNA vaccines the public needs to be aware of. This analysis showed an increased risk of cardiac-related death among men 18-39. FL will not be silent on the truth." tweeted Florida Surgeon General Dr Joseph A. Ladapo.

In line with the above observation, the Florida Department of Health has issued the following guidance citing,

"The State Surgeon General now recommends against the COVID-19 mRNA vaccines for males ages 18-39 years old."

In addition to this, the Florida Department of Health (Department) stated,

Based on currently available data, patients should be informed of the possible cardiac complications that can arise after receiving a mRNA COVID-19 vaccine. With a high level of global immunity to COVID-19, the benefit of vaccination is likely outweighed by this abnormally high risk of cardiac related death among men in this age group.

Individuals and health care providers should also be aware that this analysis found:

• Males over the age of 60 had a 10% increased risk of cardiac-related death within 28 days of mRNA vaccination.

• Non-mRNA vaccines were not found to have these increased risks among any population.