Beta-blockers may reduce infection risk in cirrhosis patients: Study
USA: The use of non-selective beta-blockers at home lowered overall risk of infections in cirrhosis patients, according to the study published in the journal Alimentary Pharmacology & Therapeutics.
The use of NSBBs is shown to reduce frequency of spontaneous bacterial peritonitis (SBP) and the enteric bacterial translocation rates in animal models. Don C. Rockey and Roula Sasso from Medical University of South Carolina, Charleston, SC, USA, aimed to evaluate the effect of NSBBs on infection‐related admissions.
For the purpose, the researchers performed a case‐control study. It included cirrhosis patients with first in‐patient admission between 1 January 2011 and 31 December 2016. The researchers examined the use of NSBB and infection development. Propensity score‐matched analysis was performed in people with NSBB use vs no use and odds ratios were calculated on this matched cohort to determine the odds of outcomes based on NSBB use.
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