Chinese native plant has antiobesity potential

Using obesity model mice, the researchers set out to verify the antiobesity effects of MFE extract and the results were remarkable. Treatment with MFE significantly suppressed the increase in body weight and adipose tissue weight, and also demonstrated morphological changes in the liver and adipose tissue of the obesity model mice. Further investigation into the mechanism revealed that fat synthesis was inhibited by suppressing the expression of several transcription factors involved in adipocyte differentiation.

“Our research group is searching for food ingredients with antiobesity effects, based on the idea that if we can find and incorporate them into our daily diets, we can contribute to people's health and longevity,” stated Professor Kojima. “These results not only suggest a link between Mallotus furetianus extract and antiobesity effects but also indicate its potential as a new food ingredient with antiobesity properties.”

Reference:

Touko Nakano, Yutaro Sasaki, Toshio Norikura, Yusuke Hosokawa, Mayu Kasano, Isao Matsui-Yuasa, Xuedan Huang, Yoshinori Kobayashi, Akiko Kojima-Yuasa, The suppression of the differentiation of adipocytes with Mallotus furetianus is regulated through the posttranslational modifications of C/EBPβ, https://doi.org/10.1002/fsn3.3551.