COVID 19 Increases Risk of hypertension disorders in pregnancy: Study
The pandemic of Coronavirus Disease 2019 (COVID-19) was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is rapidly evolving as a major threat to global health. In a recent study, researchers found that infecting with COVID-19 was causally associated with a higher risk of pregnancy hypertension. The study findings were published in the journal Pregnancy Hypertension in December 2021, issue.
Hypertensive disorders in pregnancy complicate 6–8% of pregnancies and lead to significant maternal or fetal morbidity and mortality. However, no study has focused on the association between COVID19 and hypertension disorders in pregnancy. Therefore, Dr Lu Hua and his team conducted a study to apply the Mendelian randomization (MR) design to explore the potential causal association between COVID-19 and the risk of hypertension disorders in pregnancy.
- Upon analysis, the researchers found that genetically predicted COVID-19 was significantly positively associated with hypertensive disorders in pregnancy, with an odds ratio (OR) of 1.111.
- They further found similar estimates [OR 1.098] on weighted median regression.
- They noted that both funnel plots and MR-Egger intercepts suggest no directional pleiotropic effects.
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