COVID-19 vaccines exhibits limited protection in blood cancer patients: Study
Written By : Dr Satabdi Saha
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2021-04-24 02:45 GMT | Update On 2021-04-24 07:07 GMT
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In a recent development, research has highlighted that mRNA COVID-19 vaccines may not fully protect people with the blood cancers, chronic lymphocytic leukemia ,(CLL) and multiple myeloma (MM).This was in accordance to two studies released late last week in Blood.
Because clinical trials of coronavirus vaccines didn't include people with blood cancers, who are prone to severe illness and complications, measuring their effectiveness in this population is important, the researchers said. They said a booster dose of the vaccine may be needed for CLL patients and that similar results would be expected for the Moderna vaccine, which they didn't test.
The first study found some interesting facts.
- Only 39.5% of 167 Israelis studied who had CLL had a positive antibody-mediated response to the Pfizer/BioNTech COVID-19 vaccine, compared with 100% of 53 controls.CLL patients currently undergoing cancer treatment had significantly lower response rates to the vaccine than people who had completed treatment and were in remission (16% vs 79%).
- Patients who hadn't yet begun treatment had a 55.5% immune response rate.
- Likewise, people who had completed treatment at least 1 year before vaccination had a 94% response rate, compared with 50% among those undergoing treatment within the last year.
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