HCQ Plus Prednisolone Improves Outcomes in Inflammatory Cardiomyopathy: Study
Inflammatory cardiomyopathy, often following fulminant myocarditis, is characterized by myocardial inflammation, impaired cardiac function, and increased risk of heart failure. Effective management of this condition is essential to prevent long-term complications and improve patient survival. Traditional treatment approaches often focus on supportive care, but recent research has explored immunomodulatory therapies to directly target inflammation and preserve cardiac function.
A new study investigated the efficacy of a 12-month combination therapy with hydroxychloroquine (HCQ) and prednisolone in patients diagnosed with inflammatory cardiomyopathy. The study included patients who had experienced fulminant myocarditis and demonstrated reduced left ventricular function, elevated inflammatory markers, and clinical symptoms of heart failure. The intervention group received HCQ alongside a tapering regimen of prednisolone, while outcomes were monitored through cardiac imaging, laboratory markers, and patient-reported functional status.
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