Link between fluoroquinolones and aortic aneurysm risk not strong, find JAMA studies

Results together from the two studies published in the JAMA Internal Medicine were not able to present a clear association between the use of fluoroquinolone antibiotics and the risk of aortic aneurysm or dissection.
A warning issued by FDA in 2018 had stated that fluoroquinolones can increase the occurrence of rare but serious ruptures or tears in the main artery of the body, called the aorta, which can lead to dangerous bleeding or even death.
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The first study led by Yaa-Hui Dong, National Yang-Ming University School of Pharmaceutical Science, Taipei, Taiwan, matched 5400 aortic aneurysm or dissection patients with 54,000 controls without the aortic disease. The cases and controls had similar infections in the prior 60 days. This led them to conclude that Fluoroquinolones versus other antibiotics did not increase aortic risk.
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