Nimesulide effective for acute fever management in adults, finds study

The results of the study was found to be

• The provisional diagnosis at the baseline visit reported major complaints like fever, fever with abdominal pain, body-ache, cough and myalgia.

• The mean baseline body temperature was found to be 103.2±1.5°F with a mean duration of 4.4±2.8 days significantly (p<0.0001) decreased to 99.7±1.8°F on the administration of Nimesulide.

• The liver and the renal profiles were found to be normal on records, and the side effects such as nausea and dyspepsia were reported only in 2% of patients.

Dr Arulrhaj and team concluded that "Nimesulide was found to be well-tolerated and effective as an antipyretic for acute fever management in adults during short-term use in real-world clinical practice." They also stated the study outcomes provide the necessary real-world evidence to physicians to consider Nimesulide as an alternative drug of choice to symptomatically manage the acute fever when treating a patient in out-patient department

For further information: S Arulrhaj, Mangesh Tiwaskar, Mudit Sabharwal, Rajiv Saikia, Sarfaraz Majid, Rahul Rathod, Amey Mane, Anup Petare, Ravindra Kale, KK Aggarwal "Effectiveness of Nimesulide in Acute Fever Management in Adults: Retrospective Electronic Medical Records Database Study Outcome in Outpatient Department" Journal of The Association of Physicians of India.