People with well-controlled, long-duration type 1 diabetes may still face high risk of heart disease, claims study

People who have had type 1 diabetes for more than 50 years without kidney complications may still be at substantial risk for heart disease, despite excellent control of blood pressure, cholesterol and blood sugar levels, according to a study presented Saturday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

Heart disease is a major cause of death in people with type 1 diabetes, especially in those who develop kidney complications from diabetes.

“As people with type 1 diabetes live longer due to improved medical care, a substantial proportion of these patients survive without kidney complications, but are still at high risk for heart disease,” said lead researcher Marc Gregory Yu, M.D., of the Joslin Diabetes Center and Harvard Medical School in Boston, Mass.

Yu and colleagues examined data from a patient group known as the “Medalists,” consisting of more than 1,000 individuals from across the United States who have had type 1 diabetes for over 50 years. The “Medalists” are noteworthy because only 13% have kidney complications from diabetes, and most also have excellent control of blood pressure, cholesterol, and blood sugar levels-all traditional risk factors for heart disease. Despite this, around 40% of them still report having heart disease.