PGI Chandigarh doctors discover DADA2 occurrence in adults too

This disease was known to be present with brain strokes, extensive bad skin rashes, limb gangrene and also other internal organs involvement.

The researchers led by Aman Sharma of the Department of Internal Medicine reported manifestations not known to be associated with this disease till now like haemorrhage in lungs, infarction of pancreas, a kind of brain (PRES) and heart involvement (focal myocarditis).

Sharma said it is important to recognise this entity since strokes do not recur if the treatment is started.

What Sharma's group showed for the first time was the good treatment outcomes of other disease manifestations which had not been reported previously.

Their group is also the first to report that similar biological drugs which cost much less than the innovator drugs are also effective.

This would help reduce the cost of treatment significantly.

As many of these similar biological drugs are made in India, this would muster support for the use of these drugs in this disease. This also has a global connotation as cost is a major hindrance to treatment for most of the developing world.

This paper has come online in 'Arthritis and Rheumatology', an official journal of the American College of Rheumatology.

Savita Kumari, Head of the Department of Internal Medicine, said the rheumatology unit has been at the forefront of vasculitis research in the world, and is also a much preferred treatment centre which is even recommended for vasculitis treatment by the vasculitis foundation of the US.

--IANS

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