TyG Index Found to Be Strong Predictor of Hypertension Risk, unravels study

Results

At the 140/90 mmHg threshold, the risk of hypertension was:

• 2.87 times higher (OR=2.87; 95% CI: 2.11-3.91) in the Q4 group of TyG compared to Q1.\

• 8.03 times higher (OR=8.03; 95% CI: 5.05-12.75) in the Q4 group of TyG-BMI compared to Q1.

At the 130/80 mmHg threshold, the risk of hypertension was:

• 2.93 times higher (OR=2.93; 95% CI: 2.34-3.68) in the Q4 group of TyG compared to Q1.

• wofold to 7.12-fold more risky (OR=7.12; 95% CI: 5.08-9.99) compared to the Q1 group of TyG-BMI for the Q4 group

Secondary Results:

• BMI 24.0-27.9 kg/m²

• The baseline characteristics of the participants were as follows:

• Q4 group of TyG had at the 140/90 mmHg threshold

• 2.79 times risk for hypertension and its OR=2.79; 95% CI: 1.67-4.66

• At the 130/80 mmHg threshold, the Q4 group of TyG was at risk for hypertension.

• 3.07 time risks and its OR=3.07; 95% CI: 2.05-4.60

TyG and TyG-BMI are powerful, independent predictors of hypertension in diagnosing different thresholds. Such findings serve to underpin the necessity for an early identification of such insulin resistance for its management to avoid both hypertension risk and other long-term cardiovascular outcomes.

Reference:

Hao H, Geng H, Ma M. Association Between Triglyceride Glucose Index and Hypertension According to Different Diagnostic Criteria. Int J Gen Med. 2025 Jan 6;18:43-53. doi: 10.2147/IJGM.S499194. PMID: 39801923; PMCID: PMC11720999.