Vitamin D Supplements Promising in Reducing Fatigue and Improving Immunological Factors in SLE: Study Reveals
Romania: Recent research has provided promising evidence regarding the benefits of vitamin D supplementation for individuals with systemic lupus erythematosus (SLE), a chronic autoimmune disease that often leads to debilitating symptoms such as fatigue and fluctuating disease activity.
The study, published in Cureus revealed that vitamin D supplementation at daily doses of 4000 and 8000 IU significantly increased serum vitamin D levels and complement levels while reducing fatigue, as assessed by FACIT-Fatigue and FSS scores. Additionally, the groups receiving vitamin D supplements showed a slight reduction in disease activity scores (SELENA-SLEDAI), although this change was not statistically significant.
Systemic lupus erythematosus is an autoimmune disorder marked by persistent inflammation and a range of clinical symptoms, with vitamin D deficiency proposed as a potential contributing factor. Alesandra Florescu, University of Medicine and Pharmacy of Craiova, Craiova, ROU, and colleagues sought to assess the impact of vitamin D supplementation on fatigue and disease activity in individuals with SLE.
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