Diabetes and Anuria Predict High Post-Void Residual After Kidney Transplantation: Study

Written By :  Dr. Shravani Dali
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2026-01-12 15:30 GMT   |   Update On 2026-01-13 09:19 GMT
Advertisement

A prospective study found that diabetes mellitus and anuria are significant predictors of high post-void residual following kidney transplantation in patients with end-stage kidney disease. In male recipients, larger prostate volume was also associated with a higher risk of urethral re-catheterisation, highlighting the importance of urologic risk assessment in transplant care.

This study investigated the risk factors for both high post-void residual (PVR) and the need for urinary re-catheterisation (RC) following kidney transplantation (KT). Our objectives were to develop a predictive risk model for high post-void residual and to outline a management strategy for patients who experience post-transplant elevated post-void residual. This prospective study included 110 adult patients who underwent kidney transplantation. High post-void residual was defined as > 150 mL in non-anuric patients and > 50 mL in anuric patients. Logistic regression analysis was conducted to identify predictive factors for high post-void residual. Urinary re-catheterisation was evaluated as a secondary outcome.

Advertisement
Results: High post-void residual was observed in 31 (28.2%) patients. On multivariate analysis, DM (odds ratio [OR], 3.11; 95% confidence interval [CI], 1.22–7.94; p = 0.02) and anuria before transplantation (OR, 3.80; 95% CI, 1.34–10.80; p = 0.01) were identified as significant predictors of high post-void residual. The area under the curve of the receiver operating characteristic for the risk model using these factors was 0.72 (95% CI, 0.61–0.82). Urinary re-catheterisation was required in 14 (12.7%) patients, and among male recipients, those who required re-catheterisation due to high post-void residual had significantly larger prostate volume (p = 0.003).
The present study demonstrated that DM and anuria are predictive factors for highpost-void residual and larger prostate volume in male recipients, which was associated with an increased likelihood of re-catheterisation. To prevent the following complications, post-void residual should be routinely measured, especially in patients with a history of diabetes or anuria.

Reference:

J. Kimura, B. Rawashdeh, B. Thomas, T. B. Dunn, M. Cooper, and E. Arpali, “ Risk Factors Associated With High Post-Void Residual Urine and Urethral Re-Catheterization in the Early Postoperative Period Following Kidney Transplantation.” Clinical Transplantation 39, no. 12 (2025): e70418. https://doi.org/10.1111/ctr.70418

Tags:    
Article Source : Clinical Transplantation

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Similar News