Fasting-mimicking diet may improve renoprotection in CKD patients: Study
A new study published in the journal of Science Translational Medicine showed that by lowering proteinuria and enhancing endothelial function, a fasting-mimicking diet (FMD) improved kidney function in a mouse model and encouraged renoprotection in patients with chronic kidney disease (CKD).
While many organs benefit from fasting-mimicking diets, it is unclear how FMDs directly impact podocyte function and CKD. Despite their impact on renal illness is uncertain, cycles of a fasting-mimicking diet encourage regeneration and lessen damage in the mice's pancreases, blood, stomachs, and neurological systems.
Furthermore, rats have not been used to test for an FMD. In contrast to animals with renal injury that did not receive the dietary intervention, this study demonstrated here that cycles of a recently designed low-salt FMD (LS-FMD) restored normal proteinuria and nephron structure and function in rats with puromycin-induced nephrosis.
This study created and fed CKD animal models a low-salt FMD that is comparable to what stage-III CKD patients in humans should consume each day. For 5 days a month for 3 months, the 13 clinical study participants had a plant-based meal that included unique vegetable-based soup, energy bar, energy drink, chip snack, tea, and important fatty acid and mineral-rich supplement formulations.
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