GFR decline and urinary excretion rates of sodium negatively related in CKD patients: study
The GFR rate and urinary excretion rate are negatively associated in chronic kidney disease (CKD) patients, as per new study published in the Kidney international.
Chronic kidney disease (CKD) means your kidneys are damaged and can't filter blood the way they should. The main risk factors for developing kidney disease are diabetes, high blood pressure, heart disease, and a family history of kidney failure.
Multiple 24-hour urine collections are necessary to adequately assess sodium and potassium intake. So, a group of researchers assessed kidney function decline for four years after baseline in relation to seven-time averaged 24-hour urinary sodium and potassium excretion (UNaV, UKV), their UNaV/UKV ratio, and their categorical combination in outpatients with chronic kidney disease (CKD).
This retrospective cohort study was based on 240 outpatients with baseline chronic kidney disease (CKD) stages 3-5, baseline age 20 years or more (median age 72.0 years), and a median follow-up (with interquartile range) of 2.9 (1.4– 4.0) years. Outcome was the percentage change in annual slope of estimated glomerular filtration rate (delta eGFR per year).
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