IgA vasculitis presenting as nephrotic syndrome, a complication of covid-19 vaccination
A recent study in the BMC Nephrology, by Illeon Cho and team closely warn about the concerns post covid -19 vaccination they state physicians should keep in mind the potential (re)activation of IgA vasculitis following mRNA COVID-19 vaccines and is important to closely monitor COVID-19 vaccinated patients, particularly those with autoimmune diseases.
The global COVID-19 vaccine campaign has been actively underway to overcome the COVID-19 pandemic. Backing up the strong recommendation for coronavirus disease 2019 (COVID 19) vaccination, many patients with medical comorbidities are being immunized. However, the safety of vaccination in patients with autoimmune diseases has not been well established.
There is no diagnostic tool to prove the causality between glomerulonephritis (GN) and mRNA COVID-19 vaccines. However, the consistency of case reports may be related to its pathogenesis and will help to make a hypothesis to prove the causality, which will also help manage kidney disease properly. The efficacy and safety of BNT162b2 and mRNA-1273 have been demonstrated in clinical trials and real-world studies. However, the safety of vaccination in patients with autoimmune diseases has not been well established. The current study evaluates the same.
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