Isolated Diastolic Hypertension Not Linked to Poor Outcomes in CKD Patients
A recent study published in the Kidney Medicine provided crucial insights into the management of blood pressure in patients with chronic kidney disease (CKD). The study, conducted within the Chronic Renal Insufficiency Cohort (CRIC) study, focused on isolated diastolic hypertension and its potential impact on kidney and cardiovascular outcomes.
Isolated diastolic hypertension occurs when systolic blood pressure (SBP) is controlled but diastolic blood pressure (DBP) remains high. In this study, 6.2% of the 5,621 participants exhibited isolated diastolic hypertension, defined as SBP ≤ 130 mm Hg and DBP >80 mm Hg. The reference group had normal blood pressure, defined as SBP ≤ 130 mm Hg and DBP ≤ 80 mm Hg.
The research aimed to determine whether isolated diastolic hypertension was associated with adverse kidney and cardiovascular outcomes. The findings were clear: there was no significant association between isolated diastolic hypertension and the risk of adverse kidney outcomes (such as a 50% decline in estimated glomerular filtration rate or kidney failure), composite cardiovascular events (including myocardial infarction, heart failure, stroke, or peripheral arterial disease), or all-cause mortality.
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