Rapid weight swings closely related with decreased kidney functions: Study
South Korea: Bodyweight fluctuations were strongly related to an increased risk of fast renal function decline in persons with normal kidney function, according to a recent study.
This study was conducted by Young Su Joo and team with an objective to look at the impact of body weight fluctuations on renal function degradation in a prospective cohort of people with normal kidney function. The findings of this study were published in Obesity, journal of The Obesity Society on 9th December, 2021.
For this research, data came from the Korean Genome and Epidemiology Study. Body weight fluctuations were calculated using average successive variability (ASV), which was defined as the average absolute body weight change for all subjects based on repeated assessments. Using linear regression analysis of successive estimated glomerular filtration rate (eGFR) readings for each patient, the drop in eGFR over time was computed. Rapid eGFR decline was defined as an annual average eGFR decline of more than 3 mL/min/1.73 m2.
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