Sarcopenic obesity in dialysis patients strongly and independently linked to diabetes

The key findings of this study were as follow:

1. The enrolled patients were split into four categories: normal (38.7%), obesity (18.8%), sarcopenia (26.9%), and sarcopenic obesity (15.6%).

2. Diabetes prevalence was highly skewed among the four groups, with the sarcopenic obese group (54.2%) having a greater rate than the others (25.9-33.7% ).

3. After adjusting for multiple co-founders, multivariate regression analysis revealed that diabetes was strongly and independently linked with sarcopenic obesity, but not with sarcopenia.

4. During the 76 +/- 35-month follow-up period, 100 individuals died.

5. When compared to patients in the normal and obesity groups, those with sarcopenia and sarcopenic obesity had considerably higher rates of all-cause mortality.

In conclusion, diabetes was found to be strongly and independently linked to sarcopenic obesity, with body mass indexes that were not significantly different from the normal group but significantly different from the sarcopenia group. It's worth noting that diabetes is a substantial independent predictor of all-cause mortality in sarcopenic obesity patients, regardless of the presence of obesity, sarcopenia, or sarcopenic obesity.

Reference:

Ishimura E, Okuno S, Nakatani S, Mori K, Miyawaki J, Okazaki H, Sugie N, Norimine K, Yamakawa K, Tsujimoto Y, Shoji S, Inaba M, Yamakawa T, Emoto M. Significant Association of Diabetes With Mortality of Chronic Hemodialysis Patients, Independent of the Presence of Obesity, Sarcopenia, and Sarcopenic Obesity. J Ren Nutr. 2022 Jan;32(1):94-101. doi:10.1053/j.jrn.2021.07.003.