Serum uric acid monitoring during aspirin-ticagrelor therapy benefits patients with kidney dysfunction, suggests study

Hyperuricemia” is the medical term for having high uric acid levels in your body. Uric acid is a waste product that’s created when your body breaks down chemicals called purines in food and drinks. Most uric acid dissolves in your blood, passes through your kidneys and leaves your body in your pee (urine). Hyperuricemia happens if too much uric acid stays in your body. Hyperuricemia causes uric acid to clump together in sharp crystals. These crystals can settle in your joints and cause gout, a painful form of arthritis. They can also build up in your kidneys and form kidney stones.

Uric acid (UA) is the end product of purine nucleotide metabolism, formed from the degradation of adenosine and guanine [8]. Serum uric acid (SUA) has been reported to be associated with atherosclerosis and metabolic syndrome [9,10]. Recent studies showed that SUA was an independent risk factor for early-onset coronary artery disease and coronary calcification

This study investigated whether serum uric acid levels are more elevated in the aspirin-ticagrelor group than in the aspirin-clopidogrel group.