SPS Use associated with Burden of High recurrence of Hyperkalemia: Study
Despite treatment with sodium polystyrene sulfonate (SPS), patients hospitalized with hyperkalemia have a high burden of readmissions and hyperkalemia recurrence, according to new research presented at the American Society of Nephrology's Kidney Week 2020 Reimagined virtual conference.
Sodium polystyrene sulfonate (SPS) is a common treatment option for hyperkalemia (HK) in the inpatient (IP) setting. However, the post-discharge outcomes of patients with HK treated with and without SPS in the IP setting are not well characterized.
Adult patients with ≥1 IP stay with HK (≥1 potassium [K] lab >5.0 mEq/L) were identified using electronic medical record data from the Research Action for Health Network (2012-2018). Patients treated with SPS during the IP stay were matched 1:1 to patients not treated with SPS on discharge status (dead/alive) and HK severity (most severe K lab during IP stay). Patient characteristics, K levels, HK treatments, length of stay (LOS) and death during IP stay were described. All-cause and HK-related IP readmission and HK recurrence (in any setting) within 30, 60 and 90 days post-discharge were described and compared using conditional logistic regressions.
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