Tenapanor Monotherapy effectively treats hyperphosphatemia in dialysis patients: Study

According to a recent study presented at the 58th European Renal Association-European Dialysis and Transplant Association meeting, tenapanor efficiently cures hyperphosphatemia in dialysis patients, whether administered alone or in conjunction with phosphate binders.
This is a randomized, open-label research to compare alternative strategies of starting tenapanor medication in CKD dialysis patients with hyperphosphatemia who are either phosphate binder naïve or on phosphate binder therapy.
The study was conducted by Steven Fishbane and team and it's findings were presented in the U.S National Library of Medicine on 16th September, 2021.
The goal of this study is to see if tenapanor alone or in combination with phosphate binders can achieve target serum phosphorus (s-P) levels of 5.5 mg/dL when used as the core therapy (alone or in combination with phosphate binders) for the treatment of hyperphosphatemia in patients on dialysis with chronic kidney disease (CKD). The trial included a Screening visit as well as a 10-week open-label Treatment Period (TP). Tenapanor was administered to patients during the TP at a dose of 30 mg twice daily. Tenapanor was given twice a day, before breakfast and supper.
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