1 out of 25 patients of Intracranial Aneurysm Growth have rupture with in one year: JAMA
1 out 25 patients showed ruptured intracranial aneurysm within one year of its growth, according to a study published in the JAMA Neurology.
Unruptured intracranial aneurysms not undergoing preventive endovascular or neurosurgical treatment are often monitored radiologically to detect aneurysm growth, which is associated with an increase in the risk of rupture. However, the absolute risk of aneurysm rupture after detection of growth remains unclear.
A study was conducted by Kamp L et. al to determine the absolute risk of rupture of an aneurysm after detection of growth during follow-up and to develop a prediction model for rupture.
Individual patient data were obtained from 15 international cohorts. Patients 18 years and older who had follow-up imaging for at least 1 untreated unruptured intracranial aneurysm with growth detected at follow-up imaging and with 1 day or longer of follow-up after growth were included. Fusiform or arteriovenous malformation-related aneurysms were excluded. Of the 5166 eligible patients who had follow-up imaging for intracranial aneurysms, 4827 were excluded because no aneurysm growth was detected, and 27 were excluded because they had less than 1 day follow-up after detection of growth.
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