Endovascular Thrombectomy may Yield Long-Term Benefits for Large Infarct Stroke Patients: Lancet
Researchers in a recent study indicated that endovascular thrombectomy offered long-term benefits to acute ischemic stroke patients having large vessel occlusion and large infarct. As per the 12-month follow-up analysis for the TENSION trial, prominent, lasting improvements in functional outcomes, quality of life, and overall survival were noted for acute ischemic attack patients due to large vessel occlusion. The findings were published in theResearchers in a recent study indicated that endovascular thrombectomy offered long-term benefits to acute ischemic stroke patients having large vessel occlusion and large infarct. As per the 12-month follow-up analysis for the TENSION trial, prominent, lasting improvements in functional outcomes, quality of life, and overall survival were noted for acute ischemic attack patients due to large vessel occlusion. The findings were published in the Lancet Neurology journal by Prof. Gotz Thomalla and colleagues.
The challenge persists in the management of chronic stroke, especially in patients with large infarcts. Endovascular thrombectomy had certain promising early results in recent studies, but long-term data has been scant. TENSION trailed this gap, examining for safety and effectiveness, up to 12 months, endovascular thrombectomy in patients with large infarcts.
The TENSION trial was an open-label, blinded endpoint randomized trial conducted in 40 hospitals in Europe and one in Canada. The patients were 18 years or older with acute ischemic anterior circulation stroke, large vessel occlusion identified by an Alberta Stroke Program Early Computed Tomographic Score of 3-5. Patients were randomly assigned to receive endovascular thrombectomy and medical treatment versus medical treatment alone within 12 hours of stroke onset.
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