IIT Mandi Researchers invent technique to detect Ischemic stroke-related abnormal brain characteristics
New Delhi: Innovators at the Indian Institute of Technology (IIT), Mandi has invented a method to simultaneously study the variations in nerve functions and brain blood flow associated with brain disorders such as Ischemic stroke.
The invented method helps in locating and classifying damaged sites (lesions) in the brain, brought about, or leading to neurological diseases.
Results of the study led by Dr Shubhajit Roy Chowdhury, Associate Professor, School of Computing & Electrical Engineering, IIT Mandi has been published in IEEE Journal of Translational Engineering in Health and Medicine and the team has been recently granted a US patent for the invention.
Dr Roy Chowdhury has collaborated with Dr Abhijit Das, a neurologist from the Institute of Neurosciences, Kolkata, and Dr Anirban Dutta, an Assistant Professor in Restorative Neurorehabilitation from the Department of Biomedical Engineering, University at Buffalo, USA.
The IIT Mandi team's invention is based on the fact that intricate interactions between nerve cells (neurons) and blood vessels (vasculature), called the NeuroVascular Coupling (NVC) regulates blood flow in the brain. Diseases such as Ischemic stroke adversely affects the NVC. NeuroVascular Uncoupling results in such cases, wherein, the nerve impulses do not trigger the required blood flow. Timely detection of NVC is critical for the prevention, diagnosis, and treatment of such diseases.
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