Long-term use of Statin significantly lowers intracerebral hemorrhage risk

Statin usage was linked to a decreased incidence of intracerebral hemorrhage (ICH), especially when the course of therapy was prolonged, says an article published in Neurology Journal. 

It's unclear whether taking statins causes intracerebral bleeding. In order to determine if the relationship between long-term statin exposure and ICH risk may change for distinct ICH sites, Nils Jensen Boe and colleagues undertook this investigation.

Danish national registry links were used for this investigation. All first-ever instances of ICH in people older than 55 between 2009 and 2018 were meticulously recorded in the Southern Denmark Region (population: 1.2 million). Patients with confirmed diagnoses in their medical records were divided into groups according to whether they had a lobar or non-lobar ICH, and they were matched in terms of their age, sex, and year to general population controls. To determine past statin and other pharmaceutical usage, which was categorized for recency, duration, and severity, a national prescription record was employed. We generated adjusted odds ratios (aORs) and associated 95% Confidence Intervals (CIs) for the risk of lobar and non-lobar ICH using conditional logistic regression adjusted for possible confounders.