Obesity does not protect against subarachnoid haemorrhage
Subarachnoid haemorrhage (SAH) is a life-threatening condition that kills, in contrast to other cerebrovascular disturbances, primarily healthy people of working age. Whereas smoking and high blood pressure are the most well-known risk factors associated with the condition, the role of many other lifestyle risk factors as causes of SAH has been unclear.
For a long time, obesity has been linked with a heightened risk of developing a number of diseases of the cardiovascular system, but findings pertaining to subarachnoid haemorrhage have been the opposite: the condition appears to occur at a lower frequency in overweight (body mass index 25–30) and obese individuals (body mass index >30) compared to underweight and normal-weight people. While the same observation has been repeatedly made in population-based follow-up studies, no explanation has been identified.
A study carried out by Finnish and Norwegian researchers published in the distinguished Stroke journal investigated whether obesity actually protects against subarachnoid haemorrhage. Unlike in prior studies, this was the first time that researchers comprehensively considered factors that may confound the findings, including people's smoking habits and the prevalence of hypertension.
The results were very clear: obesity does not protect against subarachnoid haemorrhage. According to Ilari Rautalin, the first author of the study, the findings provide a simple explanation of the previous observations.
https://www.ahajournals.org/doi/10.1161/STROKEAHA.121.034782
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