Doctors at Panipat Hospital give new lease of life to newborn suffering from Collodion Syndrome

The baby required oxygen support and was nursed in an incubator with 70 percent humidity. A dermatology consult was obtained, and skin emollients were initiated.

The baby's infection screen was positive, and a 2-week course of high-grade IV antibiotics was given.

Daily monitoring of weight, serum electrolytes, and input/output was performed, and IV fluids were administered to maintain hydration and prevent electrolyte imbalances.

Over time, the eyelid and lip eversion improved with the shedding of the Collodion skin membrane, the doctors said.

Genetic testing of parents showed the absence of consanguinity or family history. The doctors counselled the parents regarding the autosomal recessive inheritance pattern of most cases of congenital ichthyosis.

"This case was challenging as the infant had acquired an infection during his admission outside, and there was respiratory distress. It required multi-disciplinary management from skin and ENT specialists. With timely interventions and parents' trust in our team, we were able to save the baby's life," Parikh said.

"The infant was discharged after 10 days of NICU stay at a weight of 2.2 kg. On follow-up, the infant had an excellent skin texture and good weight gain," the doctor added.