Transforming Cancer Care: P D Hinduja Hospital launches advanced CAR-T Cell Therapy

Mumbai: P D Hinduja Hospital, Khar is set for a monumental leap in cancer care with the introduction of cutting-edge CAR-T cell therapy.

One of the first hospitals in Mumbai to collaborate with ImmunoACT, P. D. Hinduja Hospital, Khar intends to herald in a new age of cancer care in Mumbai. NexCAR19 (Actalycabtagene autoleucel) is India’s first indigenous gene-modified cell treatment for patients aged 15 and above with relapsed or refractory B-cell lymphoma and B-acute lymphoblastic leukemia.

NexCAR19™ is a CAR-T cell therapy indigenously developed and manufactured by ImmunoACT (in association with IIT-Bombay and Tata Memorial Centre). It is a breakthrough therapy that modifies immune cells, particularly T-cells, transforming them into potent cancer fighters known as CAR-T cells. This therapy, which is a 2nd generation humanized CAR-T cell therapy, is autologous (patient-specific), and targets the CD19 protein - a biomarker that is overexpressed in certain B-cell cancers.

This therapy is recommended for patients with B-cell lymphomas or B-acute lymphoblastic leukemia who have not responded to traditional therapies such as chemotherapy, resulting in a relapse or recurrence of cancer. Also called a living drug, the therapy gives considerable advantages and involves swift, single infusion treatment, improving the quality of life for many patients at almost one-tenth the cost commercially available worldwide.

Dr (Prof) Vijay Patil, Consultant, Medical Oncology at P. D. Hinduja Hospital, Khar said,” The arrival of CAR-T program in P. D. Hinduja Hospital marks the start of a new era of personalized cancer care. It opens avenues for newer therapies and solutions for patients with resistant cancers.”

Dr Ashay Karpe, Consultant, Hemato-Oncology at P. D. Hinduja Hospital, Khar said, “The CAR-T program at P. D. Hinduja Hospital will provide new hope to many cancer patients at an affordable cost, encouraging a paradigm shift in oncology that stresses both efficacy and accessibility.”

Mr. Shirish Arya, Co-founder & Director of Business Development and Corporate Strategy said, "Partnering with P.D.Hinduja Hospital and Medical Research Centre, one of Mumbai's leaders in consolidated cancer care, will allow us to broaden the accessibility of NexCAR19 to patients. We look forward to actively contributing towards better outcomes and significant improvements in patients' quality of life through this collaboration."

P. D. Hinduja Hospital, Khar, stands at the forefront of medical innovation with the introduction of NexCAR19™. The hospital’s commitment to providing the latest treatment now extends to oncology as well. With cutting-edge technology, a compassionate team, and a dedication to quality, the hospital aspires to make an eternal impact in the lives of patients by transforming innovative therapies like as CAR-T Cell Therapy into a beacon of hope for patients in Mumbai and beyond.