AstraZeneca gets CDSCO nod for new indications of Benralizumab, Osimertinib in India

Written By :  Ruchika Sharma
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2025-05-30 07:30 GMT   |   Update On 2025-05-30 07:30 GMT

Bangalore: AstraZeneca Pharma India Limited has received regulatory approval from the Central Drugs Standard Control Organisation (CDSCO) under the Directorate General of Health Services, Government of India, to import for sale and distribution of Benralizumab 30 mg/ml Solution for Injection (Brand name: Fasenra) and Osimertinib Tablets 40 mg & 80 mg (TAGRISSO) for an additional indication in India.

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With this approval, Benralizumab is now indicated as an add-on treatment for adult patients with relapsing or refractory eosinophilic granulomatosis with polyangiitis (EGPA). EGPA is a rare autoimmune disease that causes inflammation of small- to medium-sized blood vessels, often affecting the lungs, skin, and nerves.
Additionally, Osimertinib has been approved as a monotherapy for the treatment of patients with locally advanced, unresectable (stage III) 
Non-small cell lung cancer (NSCLC) whose tumours have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations and whose disease has not progressed during or following platinum based chemoradiation therapy. NSCLC is the most prevalent form of lung cancer, typically characterized by a slower growth and spread compared to small cell lung cancer.

The company stated that this regulatory nod paves the way for the marketing of Benralizumab and Osimertinib in India for the specified additional indication, subject to the receipt of related statutory approvals, if any.

Earlier, in April 2025, the Medical Dialogues team reported that AstraZeneca had received CDSCO permission to import for sale and distribute Osimertinib Tablets 40 mg and 80 mg (Tagrisso) for another additional indication. That approval allows Osimertinib to be used in combination with pemetrexed and platinum-based chemotherapy as a first-line treatment for patients with locally advanced or metastatic NSCLC whose tumours have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations.

Read also: AstraZeneca Pharma India gets CDSCO nod to import, distribute lung cancer drug Osimertinib

AstraZeneca India was established in 1979 and is headquartered at Bengaluru, Karnataka. AstraZeneca Pharma India Limited is the operating company and covers manufacturing, sales and marketing activities of the company in India.

It is a listed company and is a subsidiary of AstraZeneca Plc, UK.

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