AstraZeneca Gets CDSCO Panel Nod to Study anticancer drug Volrustomig

Monoclonal antibodies targeting the immune checkpoint proteins such as PD-1 and CTLA-4 have been around for a long time, however, due to their limited effect on the majority of patients, the idea of dual immune checkpoint inhibitors using bispecific antibodies has been gaining attention from researchers all over the world.

The drug candidate is a bi-specific monoclonal antibody. It is administered through an intravenous route. It acts by targeting programmed cell death protein 1 (PD-1) and Cytotoxic T Lymphocyte Protein 4 (CTLA4).

At the recent SEC meeting for oncology and hematology held on 21st and 22nd December 2023, the expert panel reviewed the Phase III clinical trial protocol No. D798AC00001.

After detailed deliberation, the committee recommended the grant of permission to conduct the clinical trial as presented by the firm.

Also Read: CDSCO Panel Approves AstraZeneca's Proposal for Protocol Amendment of anti-cancer drug Asciminib