Bajaj Healthcare launches COVID drug under brand name DGJAJ
The drug comes in powder form in a sachet, which is taken orally by dissolving it in water.;
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Thane: Bajaj Healthcare Limited, a manufacturer of APIs, Intermediates and Formulations has recently announced the launch of API and Formulation of "DGJAJ" (2-Deoxy-D-Glucose), an antiviral drug used for treating COVID patients, in collaboration with Defence Research and Development Organisation (DRDO). BHL had received a license agreement from DRDO on 7th July, 2021, to manufacture and market 2-Deoxy-D-Glucose (2-DG).
"The production of "DGJAJ" commenced from today onwards," the company said in a filing on Saturday.
2-Deoxy-D-glucose (2-DG) is a glucose analogue, which has the 2-hydroxyl group replaced by hydrogen. 2-DG is transported in cells by the glucose transporters on the cell membrane but it cannot undergo further glycolysis and act as inhibitor of glycolysis. Therefore, cells with higher glucose uptake, for example tumour cells, virally infected cells, inflammatory cells have also a higher uptake of 2-DG. Since, it accumulates selectively more in such cells with high glucose demand; it offers an attractive approach of inhibiting tumour cell growth, viral infection and inflammation.
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