Bayer begins Phase II trial with BAY 2927088 in metastatic or unresectable HER2 mutant solid tumors
Berlin: Bayer has announced that the first patient has been enrolled in the global Phase II panSOHO study, an open-label clinical trial, assessing the efficacy and safety of investigational agent BAY 2927088 in adult patients with metastatic or unresectable solid tumors harboring HER2-activating mutations. These include tumors of the colon or rectum, the uterus and the cervix, the bladder, and the biliary tract (includes gall bladder and bile ducts) as well as other types of solid tumors, excluding advanced non-small cell lung cancer (NSCLC).
“We are excited to initiate the panSOHO trial, which represents our ongoing commitment to precision oncology research and the development of innovative targeted therapies,” said Christian Rommel, Ph.D., Head of Research and Development at Bayer’s Pharmaceuticals Division. “This study is a critical step in evaluating a potential new treatment strategy for patients with a variety of solid tumors driven by HER2-activating mutations, who often have limited treatment options.”
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