BDR Pharma launches generic cancer drug Rucaparib in India

"BDPARIB was developed to treat patients living with advanced ovarian and prostate cancer with an unmet need. This research's positive results through the ARIEL3 study & TRITON2 study are highly promising and indicate that the benefits extend beyond the BRCAm population. This represents a significant advancement in the treatment of cancer patients in the future. Approvals for generics like Rucaparib, a PARP inhibitor, enables us to progress in this emerging era of personalized medicine and eradicate life-threatening diseases", said Mr.Dharmesh Shah, CMD, BDR Pharma

The ARIEL3 and TRITON2 study was conducted on 115 patients. Ovarian Cancer patients were enrolled between April 7, 2014, and July 19, 2016, and Prostate Cancer patients were enrolled from May 8, 2019, to December 23, 2019. Median follow-up was more than 2 years. Rucaparib significantly improved progression-free survival in patients with platinum-sensitive ovarian cancer who had achieved a response to platinum-based chemotherapy. It showed a remarkable change as a new standard of care for women with platinum-sensitive ovarian cancer following complete or partial response to second-line or later platinum-based chemotherapy in a maintenance treatment setting. The treatment demonstrated significant clinical activity in men with mCRPC associated with a BRCA alteration. The trials resulted in meaningful radiographic and PSA responses, including complete responses in soft- tissue disease.

The product is priced at MRP Rs 54,000 (Bottle of 60) for 300 Mg dose & MRP Rs 45,000 (Bottle of 60) for 200 Mg dose.