Boehringer Ingelheim partners with Ribo to develop new treatments for people with liver diseases
Written By : Ruchika Sharma
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2024-01-03 08:23 GMT | Update On 2024-03-27 07:26 GMT
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Ingelheim: Suzhou Ribo Life Science Co., Ltd. and Ribocure Pharmaceuticals AB (Ribo) have announced a collaboration with Boehringer Ingelheim to develop novel treatments for nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH).
More than 440 million people worldwide are estimated to live with NASH, an inflammatory liver disease that is caused by accumulation of fat in the liver. Over time, NASH causes scar tissue formation, which in many cases leads to liver cirrhosis and related serious complications, including liver failure or liver cancer. Currently there are no approved medicines for NASH and there is an urgent need for new effective treatment options that can prevent NASH progression and maintain and restore liver function.
Ribo’s cutting edge RIBO-GalSTAR platform enables the development of RNAi therapeutics targeting disease-causing genes specifically in hepatocytes by silencing their messenger RNAs (mRNAs). This approach has the potential to treat diseases addressing previously inaccessible drug targets.
“We look forward to working with the scientists from Ribo to develop new breakthrough medicines for patients with NASH,” said Søren Tullin, Ph.D., Senior Vice President and Global Head of Cardiometabolic Diseases Research, Boehringer Ingelheim. “This new partnership is part of our commitment to collaborate with peers worldwide to address the interconnected nature of CRM diseases. Our goal is to develop the next wave of innovative medicines that will lead to a holistic health gain for patients.”
Read also: Boehringer Ingelheim receives approval for Senvelgo in Europe for diabetic cats
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