Tuberculosis (TB) remains one of the world’s deadliest infectious diseases, claiming 1.23 million lives in 2024 alone, as reported by the WHO. Ending the TB epidemic by 2030 is a key global health priority under the United Nations Sustainable Development Goals (SDGs). However, the world continues to rely on the Bacillus Calmette Guérin (BCG) vaccine, developed over a century ago, which provides only limited protection mainly to infants and is largely ineffective in preventing pulmonary TB in adolescents and adults.
A next-generation HSP Subunit Vaccine has been developed through collaborative research led by Prof. Ashis Biswas of Indian Institute of Technology (IIT) Bhubaneswar and Dr. Sunil Kumar Raghav of Institute of Life Sciences (ILS), Bhubaneswar.
This vaccine candidate is designed to trigger strong humoral and cell-mediated immune responses while enhancing the protective efficacy of the existing BCG vaccine. In view of its significant public health potential, National Research Development Corporation (NRDC) proactively identified and evaluated this technology and facilitated the licensing process to ensure its advancement.
The technology exchange was held at ILS Bhubaneswar in the presence of several senior dignitaries including Dr. Debasis Dash, Director, ILS; Prof. Shreepad Karmalkar, Director, IIT Bhubaneswar; Prof. Dinakar Pasla, Dean (Sponsored Research & Industrial Consultancy), IIT Bhubaneswar; Dr. B. K. Sahu, Senior Regional Manager & Head – Outreach Offices, NRDC; Syed S. Ahmed, Director & CEO, TechInvention Lifecare Limited; Dr. Sunil Kumar Raghav, Scientist F, ILS Bhubaneswar; Dr. Ashis Biswas, Professor, School of Basic Sciences, IIT Bhubaneswar, along with other distinguished guests.
TechInvention Lifecare Limited, the licensed industry partner, will play a key role in translating this indigenous vaccine technology into a viable public health solution.
This partnership ensures that the jointly developed vaccine candidate advances efficiently from research to product development, validation, and eventual commercialization.
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