Lupin, I'rom ink pact for biosimilar Denosumab

Currently, Denosumab is available under two brands, Pralia and Ranmark.

Published On 2022-08-25 07:00 GMT   |   Update On 2022-08-25 07:00 GMT
Advertisement

Mumbai: Lupin Limited has entered into an exclusive licensing agreement with I'rom Group Co. Ltd, a pharmaceutical company in Japan. Under the terms of the Agreement, I'rom will conduct clinical trials along with Lupin, register, distribute and market biosimilar Denosumab in Japan on an exclusive basis.

Denosumab is indicated for the treatment of postmenopausal women with osteoporosis at high risk of fracture and prevention of skeletal-related events in patients with bone metastases from solid tumors among other indications.

Following the completion of the clinical trial and receipt of marketing authorization from PMDA in Japan, I'rom will exclusively commercialize the product in Japan.

As part of the agreement, Lupin will receive multiple milestone payments. Currently, Denosumab is available under two brands, Pralia and Ranmark, with a market size of approximately USD 500 million in Japan.

"We are pleased to partner with I'rom in Japan to bring this important biosimilar to the market. Biosimilars are a key growth driver for Lupin, and through products such as this, we are making significant progress in improving access and affordability of important treatments for patients," said Nilesh Gupta, Managing Director, Lupin.

Read also: Lupin, Accenture collaborate to accelerate business efficacy with data driven competencies

"In post-menopausal women, osteoporosis is often caused by estrogen decline and is a common condition associated with advancing age. It can result in severe clinical consequences, such as back pain and bone fractures particularly in the spine and hips," said Dr. Cyrus Karkaria, President – Biotechnology, Lupin. "In progressing our development program for denosumab biosimilar, we hope to provide patients with early and expanded access to advanced biologic medicines, which has the potential to change their course of illness."

Read also: Lupin gets USFDA nod for generic equivalent of Mylan Specialty Perforomist Inhalation Solution

Lupin is an innovation-led transnational pharmaceutical company headquartered in Mumbai, India. The Company develops and commercializes a wide range of branded and generic formulations, biotechnology products, and APIs in over 100 markets in the U.S., India, South Africa, and across the Asia Pacific (APAC), Latin America (LATAM), Europe, and Middle East regions. 

Tags:    

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Similar News