Lupin receives USFDA observations for two Pithampur manufacturing units

Written By :  Ruchika Sharma
Written By :  Dr. Kamal Kant Kohli
Published On 2025-07-18 06:27 GMT   |   Update On 2025-07-18 06:27 GMT
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Mumbai: Pharma major Lupin has received multiple observations from the U.S. Food and Drug Administration (USFDA) following inspections at two of its manufacturing facilities located in Pithampur, Madhya Pradesh.

According to a regulatory filing with the BSE, the USFDA conducted an inspection at Lupin’s Pithampur Unit-3 manufacturing facility from July 7 to July 17, 2025. The inspection concluded with the issuance of a Form-483 with three observations.

"We will address the observations and collaborate with the U.S. FDA to resolve them within the stipulated timeframe. We are committed to be compliant with CGMP quality standards across all our facilities," the company added.

In a seperate filing the company informed that the USFDA also inspected Lupin’s Pithampur Unit-2 manufacturing facility from July 08 to July 17, 2025. The inspection closed with Form-483 with four observations.
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An FDA Form 483 is issued to firm management at the conclusion of an inspection when an investigator(s) has observed any conditions that in their judgment may constitute violations of the Food Drug and Cosmetic (FD&C) Act and related Acts.

"We are addressing these observations comprehensively and will respond to the U.S. FDA within the stipulated timeframe. We uphold quality and compliance with utmost importance and are committed to be compliant with CGMP quality standards across all our facilities," Lupin said on its 
Pithampur Unit-2 manufacturing facility inspection.

Read also: Lupin arm Dabhasa facility gets GMP certification from TGA Australia

Lupin Limited is a global pharmaceutical leader headquartered in Mumbai, India, with products distributed in over 100 markets. Lupin specializes in pharmaceutical products, including branded and generic formulations, complex generics, biotechnology products, and active pharmaceutical ingredients. The company has a strong position in India and the U.S. across multiple therapy areas, including respiratory, cardiovascular, anti-diabetic, anti-infective, gastrointestinal, central nervous system, and women's health. Lupin has 15 state-of-the-art manufacturing sites and 7 research centers globally.

Read also: Lupin rolls out Loteprednol Etabonate Ophthalmic Suspension, 0.5% in US

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