Novartis Gets CDSCO Panel Nod To Study Antiparasitic drug LXE408
Written By : Dr. Divya Colin
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2025-03-07 11:45 GMT | Update On 2025-03-07 11:45 GMT
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New Delhi: Drug major Novartis has got approval from the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) to conduct the clinical study of the antiparasitic drug LXE408.
The firm presented phase 1 clinical study protocol no.: CLXE408A12105 amendment version no. 1 dated 31-January- 2025.
LXE408 is a first-in-class parasite-selective inhibitor of the kinetoplastid proteasome with potent and uniform anti-parasitic activity against all kinetoplastid parasites, including Leishmania species causing visceral leishmaniasis (L. donovani and L. infantum), as well as parasites causing Chagas disease (T. cruzi) and human African trypanosomiasis (T. brucei).
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